How do people even handle the Death Guard/Nurgle?

Most of my intricate 40k knowledge is second hand or stolen from hours of looking at the Lexicanum, so I'll be the first to admit there are already some blindspots, but from everything I've read about the Death Guard they...they just seem like a nightmare.

So I'm curious what the Imperium in particular has access to lore-wise to counter them (if anything) and how they deal with the aftermath of all the disease and rot on a logistical level.