Looking for anime for adults (NOT hentai)

I am looking to get back to watching some anime - preferably isekai or fantasy in general. The thing is ... I would like them to be aimed at adults. Not in the sence of ecchi (don't care if there's some but it shouldn't be too much), but I want the story to be for an older audience. Ideally the main characters would of course also be adults.
I did enjoy Attack on Titan and Nana a lot but other than those I haven't had much luck with anime in recent years.